Anaplastic Large-Cell Lymphoma ALK Negative (ALCLALKN)

Overview

ALK-negative Anaplastic Large-Cell Lymphoma, a subtype of ALCL within Mature T and NK Neoplasms.

Cohorts in the corpus

• mtnn_msk_2022: ALK− ALCL comprised 11% of the 132-patient MSK nodal PTCL cohort PMID:37078708.

Recurrent alterations

• Analyzed within the broader PTCL cohort where TP53 mutations/17p deletions independently predicted inferior PFS and CDKN2A deletions predicted inferior OS PMID:37078708.

Subtypes

• See parent ALCL.

Therapeutic landscape

• Curative-intent CHOP-based chemotherapy, including CHOEP/EPOCH and BV-CH(E)P PMID:37078708.

Sources

• PMID:37078708

This page was processed by crosslinker on 2026-04-10.