Pan-Cancer Analysis of Whole Genomes (PCAWG)

Unverified: PCAWG is not catalogued by cBioPortal as a studyId in schema/ontology/studies.json. This page uses a corpus-derived slug and is flagged unverified: true per the cbio-kb ontology protocol PMID:36723991.

Overview

PCAWG is the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes project, a reference pan-cancer WGS resource. Within the cbio-kb corpus, PCAWG is used as an external benchmark for whole-genome mutational burden and signature analyses rather than as a primary cohort of record PMID:36723991.

Composition

  • Approximately 2,780 tumor/normal whole genomes spanning multiple cancer types, as referenced by citing papers PMID:36723991.

Assays / panels (linked)

Papers using this cohort

  • PMID:36723991 — Maura et al. benchmarked the mutational burden of their classic Hodgkin lymphoma WGS cohort against PCAWG (n=2,780) and a multiple myeloma WGS cohort, placing cHL HRS cells (median 5,279 SBS+indels per genome) within the range of other cancers represented in PCAWG PMID:36723991.

Notable findings derived from this cohort

  • Used as a pan-cancer mutational-burden reference in cHL WGS analysis; PCAWG provided the comparator range against which cHL SBS and indel burdens were evaluated PMID:36723991.

Sources

  • Corpus-derived slug. PCAWG is not catalogued by cBioPortal, so there is no canonical studyId for this resource PMID:36723991.

This page was processed by crosslinker on 2026-04-08.