TCIA TCGA-OV CT Imaging Collection

Overview

The TCIA TCGA-OV imaging collection pairs pre-treatment contrast-enhanced CT scans with the TCGA Ovarian Serous Cystadenocarcinoma genomic cohort (ov_tcga). The imaging data is hosted on The Cancer Imaging Archive and provides the radiology component for multimodal studies requiring paired CT + genomics in HGSOC. This is a corpus-grown slug (TCIA imaging collection); it is not a cBioPortal studyId. PMID:35764743

Composition

  • Cancer type: HGSOC, predominantly stage III/IV.
  • 148 TCGA-OV patients contributed CT imaging to the Boehm et al. 2022 multimodal cohort; CT scans pulled from TCIA and paired with genomic data from cBioPortal ov_tcga. PMID:35764743
  • CT scans: pre-treatment contrast-enhanced abdominal/pelvic CT (median 120 kVp, 5 mm slice thickness); segmented by three fellowship-trained gynecologic radiologists using ITK-SNAP v3.8.0 for adnexal masses and omental implants. PMID:35764743

Assays / panels (linked)

  • Pre-treatment contrast-enhanced CT imaging (adnexal and omental lesion segmentation).

Papers using this cohort

  • PMID:35764743 — Boehm et al. 2022, Nature Cancer: CT imaging from TCIA-TCGA-OV used as the radiology component for the 148 TCGA-OV patients in the multimodal HGSOC late-fusion prognostic study.

Notable findings derived from this cohort

  • Omental CT radiomics (Coif-wavelet GLCM autocorrelation, HLL wavelet) were prognostically informative (test c-index 0.53); adnexal radiomics were not significant after Benjamini–Hochberg correction. PMID:35764743
  • TCGA-OV CT scans acquired on varying scanner hardware relative to MSKCC scans (GE Medical Systems); the omental radiomic feature identified as prognostic was invariant to CT vendor and segmenting radiologist. PMID:35764743

Sources

  • TCIA collection: TCGA-OV — https://www.cancerimagingarchive.net/collection/tcga-ov/
  • PMID:35764743 — Boehm et al. 2022, Nature Cancer.

This page was processed by crosslinker on 2026-05-04.