INC-B099280

Overview

INC-B099280 is an investigational anti-BTLA (B and T lymphocyte attenuator) antibody targeting BTLA, an inhibitory receptor implicated in T-cell exhaustion. It is evaluated in nasopharyngeal carcinoma (NPC).

Evidence in the corpus

  • INC-B099280 anti-BTLA antibody listed as an investigational agent targeting compensatory BTLA-mediated checkpoint upregulation in recurrent/metastatic NPC T-cell exhaustion context PMID:24952746.

Resistance mechanisms

Cancer types (linked)

Sources

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