INC-B099280
Overview
INC-B099280 is an investigational anti-BTLA (B and T lymphocyte attenuator) antibody targeting BTLA, an inhibitory receptor implicated in T-cell exhaustion. It is evaluated in nasopharyngeal carcinoma (NPC).
Evidence in the corpus
- INC-B099280 anti-BTLA antibody listed as an investigational agent targeting compensatory BTLA-mediated checkpoint upregulation in recurrent/metastatic NPC T-cell exhaustion context PMID:24952746.
Resistance mechanisms
Cancer types (linked)
Sources
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