CADM2

Overview

CADM2 (Cell Adhesion Molecule 2) is a synaptic cell adhesion molecule implicated in neuronal connectivity and tumor suppression. It has been observed as a focal deletion target in cancer genomic studies.

Alterations observed in the corpus

• Highlighted in TieDIE/focal-deletion analyses as a downstream pathway and SCNA feature in CCRCC (TCGA, n=446) PMID:23792563

Cancer types (linked)

• Clear cell renal cell carcinoma (CCRCC): focal deletion observed in TCGA cohort PMID:23792563

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:23792563

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