CD99

Overview

CD99 is a cell-surface glycoprotein that is constitutively highly expressed in Ewing sarcoma and is used as a diagnostic marker for the disease. Its expression is independent of the EWS::FLI1 fusion oncogene.

Alterations observed in the corpus

• Constitutive Ewing sarcoma marker; expression unaffected by EWS::FLI1 introduction in heMSCs (cell-of-origin model) PMID:25186949

Cancer types (linked)

• Ewing sarcoma: constitutive marker, expression independent of EWS::FLI1 PMID:25186949

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:25186949

This page was processed by entity-page-writer on 2026-05-11.