ELF3

Overview

ELF3 (E74-Like ETS Transcription Factor 3) is an ETS family transcription factor. ELF3 LOF mutations are recurrent in gallbladder carcinoma (GBC) and represent one of the more frequent driver events in this disease.

Alterations observed in the corpus

• ELF3 LOF mutations in 9% of GBC PMID:36228155
• ELF3 identified as a novel significantly mutated gene (SMG) in 8% of muscle-invasive bladder cancers in TCGA urothelial carcinoma comprehensive genomic characterization PMID:24476821
• Mentioned in study PMID:26804919

Cancer types (linked)

• GBC: LOF mutations in 9% of cases; one of the more frequent driver mutations PMID:36228155

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:36228155

This page was processed by crosslinker on 2026-05-09. - PMID:24476821

This page was processed by crosslinker on 2026-05-09. - PMID:26804919

This page was processed by wiki-cli on 2026-05-14.