FGF9
Overview
FGF9 (Fibroblast Growth Factor 9) is a secreted signaling protein that activates FGFR receptors to promote proliferation, survival, and differentiation. FGF9 maps to chromosome 13q12, a region subject to focal copy-number loss in anaplastic thyroid carcinoma.
Alterations observed in the corpus
- Focal copy-number loss on chromosome 13 affecting FGF9 in anaplastic thyroid carcinoma (ATC); co-localized loss with FLT3 at the same chromosomal region PMID:38412093.
Cancer types (linked)
- THAP — focal CNA loss on chromosome 13 PMID:38412093.
Co-occurrence and mutual exclusivity
- Co-deleted with FLT3 in ATC (chromosome 13 focal loss) PMID:38412093.
Therapeutic relevance
- Not reported in the corpus.
Open questions
- Whether FGF9 loss contributes to ATC biology independently of the co-deleted FLT3 is unresolved PMID:38412093.
Sources
This page was processed by crosslinker on 2026-05-04.