INO80
Overview
INO80 encodes a chromatin-remodeling ATPase. In the cbio-kb corpus it was nominated as a novel CLL driver.
Alterations observed in the corpus
- Novel CLL driver with mutations clustered in the DNA-binding domain PMID:35927489.
Cancer types (linked)
- CLLSLL — nominated as a candidate driver in the CLL map cohort (n=1,148) PMID:35927489.
Co-occurrence and mutual exclusivity
- None reported.
Therapeutic relevance
- None reported.
Open questions
- Functional validation of INO80 as a CLL driver is deferred to future work PMID:35927489.
Sources
This page was processed by crosslinker on 2026-04-08.