RAD51D

Overview

RAD51D is a member of the RAD51 paralog family involved in homologous recombination DNA repair. Germline RAD51D mutations are associated with increased ovarian and breast cancer risk.

Alterations observed in the corpus

• RAD51D assessed in gallbladder carcinoma (GBC) genomic landscape study as part of the HRD gene panel PMID:36228155

Cancer types (linked)

• GBC: assessed as part of HRD-related gene panel in MSK-IMPACT profiling PMID:36228155

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:36228155

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