RAMP3

Overview

RAMP3 (Receptor Activity-Modifying Protein 3) is a single-pass transmembrane protein involved in modifying the pharmacology and trafficking of G protein-coupled receptors. In cancer genomics, it has been identified as a component of a prognostic gene expression signature in hepatocellular carcinoma.

Alterations observed in the corpus

  • RAMP3 is part of a 5-gene tumor score (TAF9, RAN, RAMP3, KRT19, HN1) that predicts HCC recurrence and survival after resection PMID:24735922

Cancer types (linked)

  • Hepatocellular carcinoma (HCC): component of a recurrence-prediction gene score PMID:24735922

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

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