RFX7
Overview
RFX7 is a regulatory factor X family transcription factor. In the corpus it is nominated as a novel U-CLL driver with adverse prognostic impact.
Alterations observed in the corpus
- Novel U-CLL driver associated with poor FFS/OS in the 1,148-patient CLL map PMID:35927489.
Cancer types (linked)
- Chronic lymphocytic leukemia (CLLSLL) — novel U-CLL-enriched driver PMID:35927489.
Co-occurrence and mutual exclusivity
- Enriched in IGHV-unmutated (U-CLL) subtype PMID:35927489.
Therapeutic relevance
- No direct therapeutic link reported in the corpus.
Open questions
- Functional validation of RFX7 as a CLL driver is deferred to future work PMID:35927489.
Sources
This page was processed by crosslinker on 2026-04-08.