SLCO1B3

Overview

SLCO1B3 (Solute Carrier Organic Anion Transporter Family Member 1B3) encodes a hepatic bile acid transporter involved in the uptake of bile salts and other organic anions. It serves as a prognostic marker of the bile-acid-active cholangiocarcinoma subtype, reflecting the role of bile acid homeostasis in CCA biology.

Alterations observed in the corpus

  • Prognostic marker of the bile-acid-active cholangiocarcinoma (CCA) subtype (identified in reviewed literature within a comprehensive CCA review) PMID:25608663

Cancer types (linked)

  • Cholangiocarcinoma (CCA): Prognostic marker of the bile-acid-active CCA subtype PMID:25608663

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

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