SNX25

Overview

SNX25 (Sorting Nexin 25) is a member of the sorting nexin family involved in intracellular trafficking. It was identified as an additional MutSig/inactivation-bias hit in aggressive cutaneous squamous cell carcinoma.

Alterations observed in the corpus

• SNX25 identified as an additional MutSig/inactivation-bias hit in aggressive cSCC (39 patients, whole exome sequencing) PMID:25303977

Cancer types (linked)

• cSCC — identified by inactivation-bias significance methods PMID:25303977

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:25303977

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