TFEC

Overview

TFEC (Transcription Factor EC) is a member of the MiTF/TFE family of basic helix-loop-helix leucine zipper transcription factors. It is discussed in the context of MiTF-family biology in non-clear cell renal carcinoma research.

Alterations observed in the corpus

• TFEC referenced as part of the MiTF-family group (alongside MITF, TFE3, TFEB) in the context of the MiTF-high subtype in non-clear cell renal carcinomas PMID:25401301

Cancer types (linked)

• nccRCC — MiTF-family context; specific TFEC somatic alterations not reported in this cohort PMID:25401301

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:25401301

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