UBE4B

Overview

UBE4B (Ubiquitination Factor E4B) is an E3/E4 ubiquitin ligase involved in protein ubiquitination and degradation. A GWAS susceptibility locus at UBE4B has been associated with HBV- or HCV-related hepatocellular carcinoma risk.

Alterations observed in the corpus

• UBE4B is a GWAS susceptibility locus/SNP associated with HBV- or HCV-related HCC risk PMID:24735922

Cancer types (linked)

• Hepatocellular carcinoma (HCC): germline susceptibility locus in viral hepatitis-related HCC PMID:24735922

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

Sources

• PMID:24735922

This page was processed by entity-page-writer on 2026-05-11.