ZC3H18

Overview

ZC3H18 is a novel M-CLL driver nominated in the CLL map cohort and associated with inferior failure-free survival.

Alterations observed in the corpus

  • ZC3H18 was identified as a novel M-CLL driver associated with short failure-free survival in the integrated CLL map cohort PMID:35927489.
  • ZC3H18 is a candidate novel prognostic marker (alongside 5q32 loss and 15q25.2 loss) for addition to CLL risk models PMID:35927489.

Cancer types (linked)

Co-occurrence and mutual exclusivity

  • Not reported in the corpus.

Therapeutic relevance

  • No direct targeted therapy reported in the corpus.

Open questions

  • Validation in independent CLL cohorts is needed before clinical use PMID:35927489.

Sources

This page was processed by crosslinker on 2026-04-08.