Illumina GoldenGate

Overview

An assay platform used for high-throughput analysis of DNA methylation or SNP genotyping.

Used by

• Used for DNA methylation profiling across 1,505 CpG sites in 206 glioblastoma cases PMID:18772890.
• Applied to 238 GBM samples for DNA methylation profiling as part of the TCGA GBM multi-platform analysis defining G-CIMP and methylation subclasses M1–M6 PMID:24120142

Notes

• Identified MGMT promoter methylation as a key feature in glioblastoma, particularly in the context of treatment response and hypermutator phenotypes PMID:18772890.

Sources

• PMID:18772890

This page was processed by crosslinker on 2026-05-09. - PMID:24120142

This page was processed by crosslinker on 2026-05-09.