FPR1

Overview

FPR1 (Formyl Peptide Receptor 1) is a G protein-coupled receptor involved in innate immune signaling. It was identified as a significantly mutated gene in small cell lung cancer (SCLC), though its functional significance in that context remains unclear.

Alterations observed in the corpus

Cancer types (linked)

Co-occurrence and mutual exclusivity

Therapeutic relevance

Open questions

  • Biological role in SCLC pathogenesis is unclear; functional experiments required PMID:26168399

Sources

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