GZMB
Overview
GZMB encodes granzyme B, the principal pro-apoptotic serine protease of cytotoxic T cells and NK cells.
Alterations observed in the corpus
- Effector cytotoxic component of the 20-gene ICR signature in colon cancer PMID:37202560.
Cancer types (linked)
- COAD — ICR component in the AC-ICAM cohort PMID:37202560.
Co-occurrence and mutual exclusivity
- Co-expressed with GNLY, PRF1, GZMA, GZMH PMID:37202560.
Therapeutic relevance
- Component of the ICR prognostic immune module PMID:37202560.
Open questions
- None flagged in the corpus.
Sources
This page was processed by crosslinker on 2026-04-08.