GZMH

Overview

GZMH encodes granzyme H, a cytotoxic lymphocyte serine protease.

Alterations observed in the corpus

• Effector cytotoxic component of the 20-gene ICR signature in colon cancer PMID:37202560.

Cancer types (linked)

• COAD — ICR component in the AC-ICAM cohort PMID:37202560.

Co-occurrence and mutual exclusivity

• Co-expressed with GNLY, PRF1, GZMA, GZMB PMID:37202560.

Therapeutic relevance

• Component of the ICR prognostic immune module PMID:37202560.

Open questions

• None flagged in the corpus.

Sources

• PMID:37202560

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